Assessment of Effects of Age and Gender on the Incubation Period of COVID-19 with a Mixture Regression Model
Volume 19, Issue 2 (2021): Special issue: Continued Data Science Contributions to COVID-19 Pandemic, pp. 253–268
Pub. online: 7 May 2021
Type: Statistical Data Science
Received
1 April 2020
1 April 2020
Accepted
1 May 2020
1 May 2020
Published
7 May 2021
7 May 2021
Abstract
Following the outbreak of COVID-19, various containment measures have been taken, including the use of quarantine. At present, the quarantine period is the same for everyone, since it is implicitly assumed that the incubation period distribution of COVID-19 is the same regardless of age or gender. For testing the effects of age and gender on the incubation period of COVID-19, a novel two-component mixture regression model is proposed. An expectation-maximization (EM) algorithm is adopted to obtain estimates of the parameters of interest, and the simulation results show that the proposed method outperforms the simple regression method and has robustness. The proposed method is applied to a Zhejiang COVID-19 dataset, and it is found that age and gender statistically have no effect on the incubation period of COVID-19, which indicates that the quarantine measure currently in operation is reasonable.
Supplementary material
Supplementary MaterialThe Supplementary Material including the detailed proofs of Theorems 1 and 2, can be found on the Journal of Data Science website. The data/code used in the analyses can be found at https://github.com/SimonsZheng/Assessment-of-Effects-of-Age-and-Gender-on-COVID-19.
References
Linton NM, Kobayashi T, Yang YC, Hayashi K, Akhmetzhanov A, Jung SM, et al. (2020). Incubation period and other epidemiological characteristics of 2019 Novel Coronavirus infections with right truncation: A statistical analysis of publicly available case data. Journal of Clinical Medicine, 9(2): 538.