Journal of Data Science

In this paper, we consider functional varying coefficient model in present of a time invariant covariate for sparse longitudinal data contaminated with some measurement errors. We propose a regularization method to estimate the slope function based on a reproducing kernel Hilbert space approach. As we will see, our procedure is easy to implement. Our simulation results show that the procedure performs well, especially when either sampling frequency or sample size increases. Applications of our method are illustrated in an analysis of a longitudinal CD4+ count dataset from an HIV study.