Abstract:In medical literature, researchers suggested various statistical procedures to estimate the parameters in claim count or frequency model. In the recent years, the Poisson regression model has been widely used particularly. However, it is also recognized that the count or frequency data in medical practice often display over-dispersion, i.e., a situation where the variance of the response variable exceeds the mean. Inappropriate imposition of the Poisson may underestimate the standart errors and overstate the significance of the regression parameters, and consequently, giving misleading inference about the regression parameters. This article suggests the Negative Binomial (NB) and Conway-Maxwell-Poisson (COM-Poisson) regression models as an alternatives for handling overdispersion. All mentioned regression models are applied to simulation data and dataset of hospitalization number of people with schizophrenia, the results are compared.