Journal of Data Science

Mediation analysis plays an important role in many research fields, yet it is very challenging to perform estimation and hypothesis testing for high-dimensional mediation effects. We develop a user-friendly $\mathsf{R}$ package HIMA for high-dimensional mediation analysis with varying mediator and outcome specifications. The HIMA package is a comprehensive tool that accommodates various types of high-dimensional mediation models. This paper offers an overview of the functions within HIMA and demonstrates the practical utility of HIMA through simulated datasets. The HIMA package is publicly available from the Comprehensive $\mathsf{R}$ Archive Network at https://CRAN.R-project.org/package=HIMA.