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Testing for COVID-19: Some Statistical Issues
Volume 19, Issue 2 (2021): Special issue: Continued Data Science Contributions to COVID-19 Pandemic, pp. 243–252
Grace Y. Yi   Wenqing He   Dennis K. J. Lin     All authors (4)

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https://doi.org/10.6339/21-JDS993
Pub. online: 7 May 2021      Type: Data Science In Action     

Received
1 June 2020
Accepted
1 September 2020
Published
7 May 2021

Abstract

The swift spread of the novel coronavirus is largely attributed to its stealthy transmissions in which infected patients may be asymptomatic or exhibit only flu-like symptoms in the early stage. Undetected transmissions present a remarkable challenge for the containment of the virus and pose an appalling threat to the public. An urgent question is on testing of the coronavirus. In this paper, we evaluate the situation from the statistical viewpoint by discussing the accuracy of test procedures and stress the importance of rationally interpreting test results.

Supplementary material

 Supplementary Material
The Diamond Princess data and the R code for the figures in the paper are available online at the Journal of Data Science website.

References

 
BioMedomics (2020). COVID-19 rapid test. https://www.biomedomics.com/products/infectious-disease/covid-19-rt/.
 
Diamond Princess (2020). Diamond princess updates. https://www.princess.com/news/notices%20_and_advisories/notices/diamond-princess-update.html.
 
Watson J, Whiting PF, Brush JE (2020). Interpreting a Covid-19 test result. BMJ, 369.
 
Woloshin S, Patel N, Kesselheim AS (2020). False negative tests for SARS-CoV-2 infection—challenges and implications. New England Journal of Medicine, 383(6): e38.
 
Wong JE, Leo YS, Tan CC (2020). COVID-19 in Singapore—current experience: Critical global issues that require attention and action. JAMA, 323(13): 1243–1244.
 
Xiao Y, Torok ME (2020). Taking the right measures to control COVID-19. The Lancet Infectious Diseases, 20(5): 523–524.
 
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. The lancet, 395(10229).

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Keywords
COVID-19 false negative false positive pandemic repeatedly testing

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