Abstract: Graphical procedures can be useful for illustrating and evaluating the process of inverse regression. We first review some simple and well-known graphical approaches for univariate linear and nonlinear models. We then propose a new graphical tool applicable to situations where the response is bivariate and repeated measures data are available. The proposed method is illustrated with an example of the age determination of tern chicks using measurements on body weight and wing length.
Abstract: Frailty models have become popular in survival analysis for deal ing with situations where groups of observations are correlated. If the data comprise only exact or right-censored failure times, inference can be done by either integrating out the frailties directly or by using the EM algorithm. If there is both left- and right-censoring this is no longer the case. How ever the MCMC method of Clayton (1991, Biometrics 47, 467-485) can be easily extended by imputation of the left-censored times. Several schemes for doing this are suggested and compared. Application of the methods is illustrated using data on the joint failures of patients with fibrodysplasia ossificans progressiva.