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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JDS</journal-id>
      <journal-title-group>
        <journal-title>Journal of Data Science</journal-title>
      </journal-title-group>
      <issn pub-type="epub">1680-743X</issn>
      <issn pub-type="ppub">1680-743X</issn>
      <publisher>
        <publisher-name>SOSRUC</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">080309</article-id>
      <article-id pub-id-type="doi">10.6339/JDS.2010.08(3).613
</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Research Article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Bimodality of Plasma Glucose Distributions in Whites: A Bootstrap Approach to Testing Mixture Models</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Yang</surname>
            <given-names>Ying</given-names>
          </name>
          <xref ref-type="aff" rid="j_JDS_aff_000"/>
        </contrib>
        <aff id="j_JDS_aff_000">University of California at Davis</aff>
        <contrib contrib-type="author">
          <name>
            <surname>Fan</surname>
            <given-names>Juanjuan</given-names>
          </name>
          <xref ref-type="aff" rid="j_JDS_aff_001"/>
        </contrib>
        <aff id="j_JDS_aff_001">San Diego State University</aff>
        <contrib contrib-type="author">
          <name>
            <surname>May</surname>
            <given-names>Susanne</given-names>
          </name>
          <xref ref-type="aff" rid="j_JDS_aff_002"/>
        </contrib>
        <aff id="j_JDS_aff_002">University of Washington</aff>
      </contrib-group>
      <volume>8</volume>
      <issue>3</issue>
      <fpage>483</fpage>
      <lpage>493</lpage>
      <permissions>
        <ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/>
      </permissions>
      <abstract>
        <p>Abstract: The null distribution of the likelihood ratio test (LRT) of a onecomponent normal model versus two-component normal mixture model is</p>
        <p>unknown. In this paper, we take a bootstrap approach to the likelihood ratio</p>
        <p>test for testing bimodality of plasma glucose concentrations from Rancho</p>
        <p>Bernardo Diabetes Study. The small p-values from this approach support the</p>
        <p>hypothesis that a bimodal normal mixture model fits the data significantly</p>
        <p>better than a unimodal normal model. The size and power of the bootstrap</p>
        <p>based LRT are evaluated through simulations. The results suggest that a</p>
        <p>sample size of close to 500 would be necessary in order to attain a power of</p>
        <p>90% for detecting the unbalanced mixtures with means and variances similar</p>
        <p>to those in the Rancho Bernardo data. Besides sample size, the power also</p>
        <p>depends on the two means and variances of the two components in the data.</p>
      </abstract>
      <kwd-group>
        <label>Keywords</label>
        <kwd>EM algorithm</kwd>
        <kwd>likelihood ratio test</kwd>
        <kwd>mixture models</kwd>
      </kwd-group>
    </article-meta>
  </front>
</article>
