Abstract: It is important to estimate transmissibility of influenza virus during its growing phase for understanding the propagation of the virus. The estimation procedures of the transmissibility are usually based on the data generated in flu seasons. The data-generating process of the outbreak of influenza has many features. The data is generated by not only a biological process but also control measures such as flu vaccination. The estimation is discussed by considering the aspects of the data-generating process and using the model to capture the essential characteristics of flu transmission during the growing phase of a flu season.