Abstract: Quick identification of severe injury crashes can help Emergency Medical Services (EMS) better allocate their scarce resources to improve the survival of severely injured crash victims by providing them with a fast and timely response. Data broadcast from a vehicle’s Event Data Recorder (EDR) provide an opportunity to capture crash information and send them to EMS near real-time. A key feature of EDR data is a longitudinal measure of crash deceleration. We used functional data analysis (FDA) to ascertain key features of the deceleration trajectories (absolute integral, absolute in- tegral of its slope, and residual variance) to develop and verify a risk predic- tion model for serious (AIS 3+) injuries. We used data from the 2002-2012 EDR reports and the National Highway and National Automotive Sampling System (NASS) Crashworthiness Data System (CDS) datasets available on the National Transportation Safety Administration (NHTSA) website. We consider a variety of approaches to model deceleration data, including non- penalized and penalized splines and a variable selection method, ultimately obtaining a model with a weighted AUC of 0.93. A novel feature of our approach is the use of residual variance as a measure of predictive risk. Our model can be viewed as an important first step towards developing a real- time prediction model capable of predicting the risk of severe injury in any motor vehicle crash.