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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">JDS</journal-id>
<journal-title-group><journal-title>Journal of Data Science</journal-title></journal-title-group>
<issn pub-type="epub">1683-8602</issn><issn pub-type="ppub">1680-743X</issn><issn-l>1680-743X</issn-l>
<publisher>
<publisher-name>School of Statistics, Renmin University of China</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">JDS1105</article-id>
<article-id pub-id-type="doi">10.6339/23-JDS1105</article-id>
<article-categories><subj-group subj-group-type="heading">
<subject>Data Science in Action</subject></subj-group></article-categories>
<title-group>
<article-title>Incorporating Interventions to an Extended SEIRD Model with Vaccination: Application to COVID-19 in Qatar</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Amona</surname><given-names>Elizabeth B.</given-names></name><xref ref-type="aff" rid="j_jds1105_aff_001">1</xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Ghanam</surname><given-names>Ryad A.</given-names></name><xref ref-type="aff" rid="j_jds1105_aff_002">2</xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Boone</surname><given-names>Edward L.</given-names></name><xref ref-type="aff" rid="j_jds1105_aff_001">1</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4960-7984</contrib-id>
<name><surname>Sahoo</surname><given-names>Indranil</given-names></name><email xlink:href="mailto:sahooi@vcu.edu">sahooi@vcu.edu</email><xref ref-type="aff" rid="j_jds1105_aff_001">1</xref><xref ref-type="corresp" rid="cor1">∗</xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Abu-Raddad</surname><given-names>Laith J.</given-names></name><xref ref-type="aff" rid="j_jds1105_aff_003">3</xref>
</contrib>
<aff id="j_jds1105_aff_001"><label>1</label>Department of Statistical Sciences and Operations Research, <institution>Virginia Commonwealth University</institution>, Richmond, Virginia, 23284, <country>USA</country></aff>
<aff id="j_jds1105_aff_002"><label>2</label>Department of Liberal Arts and Sciences, <institution>Virginia Commonwealth University in Qatar</institution>, Education City, Doha, <country>Qatar</country></aff>
<aff id="j_jds1105_aff_003"><label>3</label><institution>Weill Cornell Medicine</institution>, <country>Qatar</country></aff>
</contrib-group>
<author-notes>
<corresp id="cor1"><label>∗</label>Corresponding author. Email: <ext-link ext-link-type="uri" xlink:href="mailto:sahooi@vcu.edu">sahooi@vcu.edu</ext-link>.</corresp>
</author-notes>
<pub-date pub-type="ppub"><year>2024</year></pub-date><pub-date pub-type="epub"><day>13</day><month>6</month><year>2023</year></pub-date><volume>22</volume><issue>1</issue><fpage>97</fpage><lpage>115</lpage><supplementary-material id="S1" content-type="document" xlink:href="jds1105_s001.pdf" mimetype="application" mime-subtype="pdf">
<caption>
<title>Supplementary Material</title>
<p>The supplementary material contains the functional form of the posterior distribution of the model parameters, a discussion on the behavior of <inline-formula id="j_jds1105_ineq_001"><alternatives><mml:math><mml:mstyle>
<mml:msub>
<mml:mrow>
<mml:mi mathvariant="fraktur">R</mml:mi>
</mml:mrow>
<mml:mrow>
<mml:mi mathvariant="fraktur">e</mml:mi>
</mml:mrow>
</mml:msub></mml:mstyle>
<mml:mo mathvariant="normal" fence="true" stretchy="false">(</mml:mo>
<mml:mi mathvariant="italic">t</mml:mi>
<mml:mo mathvariant="normal" fence="true" stretchy="false">)</mml:mo></mml:math><tex-math><![CDATA[${\mathfrak{R}_{\mathfrak{e}}}(t)$]]></tex-math></alternatives></inline-formula> over time, and some trace plots validating convergence of model parameters. The dataset and code used for this project can be found at <uri>https://github.com/elizabethamona/SEIRDV-model</uri>.</p>
</caption>
</supplementary-material><history><date date-type="received"><day>28</day><month>10</month><year>2022</year></date><date date-type="accepted"><day>14</day><month>5</month><year>2023</year></date></history>
<permissions><copyright-statement>2024 The Author(s). Published by the School of Statistics and the Center for Applied Statistics, Renmin University of China.</copyright-statement><copyright-year>2024</copyright-year>
<license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
<license-p>Open access article under the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">CC BY</ext-link> license.</license-p></license></permissions>
<abstract>
<p>The COVID-19 outbreak of 2020 has required many governments to develop and adopt mathematical-statistical models of the pandemic for policy and planning purposes. To this end, this work provides a tutorial on building a compartmental model using Susceptible, Exposed, Infected, Recovered, Deaths and Vaccinated (SEIRDV) status through time. The proposed model uses interventions to quantify the impact of various government attempts made to slow the spread of the virus. Furthermore, a vaccination parameter is also incorporated in the model, which is inactive until the time the vaccine is deployed. A Bayesian framework is utilized to perform both parameter estimation and prediction. Predictions are made to determine when the peak Active Infections occur. We provide inferential frameworks for assessing the effects of government interventions on the dynamic progression of the pandemic, including the impact of vaccination. The proposed model also allows for quantification of number of excess deaths averted over the study period due to vaccination.</p>
</abstract>
<kwd-group>
<label>Keywords</label>
<kwd>Bayesian statistics</kwd>
<kwd>compartmental model</kwd>
<kwd>epidemiology</kwd>
<kwd>intervention analysis</kwd>
<kwd>reproduction number</kwd>
</kwd-group>
</article-meta>
</front>
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